SCHEMBL21836690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21836694	0.86	MAPT (0.42)	KDM4EHPGDGAATP53SMN1; SMN2
	SCHEMBL21836666	0.83	UGCG (0.44)	KDM4EHPGDGAAMAPTLMNA
	SCHEMBL22344794	0.75	POLB (0.40)	HPGDMAPTTSHRLMNAALDH1A1
	SCHEMBL29445731	0.74	PTGER4 (0.54)	KDM4EHPGDGAASMN1; SMN2MAPT
	SCHEMBL21836697	0.74	MAPT (0.46)	KDM4EHPGDGAATP53MAPT
	SCHEMBL21836678	0.72	POLB (0.50)	KDM4EHPGDGAAMAPTTSHR
	SCHEMBL26690229	0.72	MAPT (0.43)	KDM4EHPGDGAATP53SMN1; SMN2
	SCHEMBL21191871	0.71	ALDH1A1 (0.43)	KDM4EHPGDGAASMN1; SMN2MAPT
	SCHEMBL21192221	0.71	TP53 (0.46)	KDM4EHPGDTP53SMN1; SMN2MAPT
	SCHEMBL26690358	0.70	POLB (0.60)	KDM4EHPGDGAAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.