Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410413 | 0.90 | MKNK1 (0.41) | PTGS2MKNK1GRM5CYP2A6GRM4 | |
| SCHEMBL12410493 | 0.87 | MKNK1 (0.39) | IDH1PTGS2MKNK1GRM5CYP2A6 | |
| SCHEMBL12709540 | 0.87 | RIPK2 (0.38) | MKNK1GRM5CYP2A6GRM4MEN1 | |
| SCHEMBL12410578 | 0.87 | GABRA1 (0.39) | IDH1MKNK1GRM5GABRA1GABRG2 | |
| SCHEMBL1555181 | 0.84 | MKNK1 (0.41) | MKNK1GRM5GRM4ADORA2AADORA2B | |
| SCHEMBL12410437 | 0.84 | IRAK4 (0.37) | IDH1PTGS2MKNK1CYP2A6GRM4 | |
| SCHEMBL12410569 | 0.83 | CYP2A6 (0.42) | MKNK1GRM5CYP2A6GRM4ADORA2A | |
| SCHEMBL12410479 | 0.82 | SMN1; SMN2 (0.40) | MKNK1GRM5GRM4GABRA1GABRG2 | |
| SCHEMBL12410407 | 0.81 | MKNK1 (0.40) | MKNK1GRM5CYP2A6GRM4MEN1 | |
| SCHEMBL12410430 | 0.81 | GRM4 (0.41) | PTGS2CYP2A6GRM4MAT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| EP-2488030-B1 | 1-(PYRID-3-YL)-PYRAZOLES AND 1-(PYRIMID-5-YL)-PYRAZOLES AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2015-01-07 | — | — | EP | disclosed |
| EP-2488030-B1 | 1-(PYRID-3-YL)-PYRAZOLES AND 1-(PYRIMID-5-YL)-PYRAZOLES AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2015-01-07 | — | — | EP | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2012116246-A2 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012116246-A2 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | WO | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| WO-2011045224-A1 | 1- (PYRID-3-YL) -PYRAZOLE AND 1- (PYRIMID-5-YL) -PYRAZOLE AS PESTICIDE | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | IDH1 442/4885PTGS2 2097/4885MKNK1 2220/4885 |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | IDH1 442/4885PTGS2 2097/4885MKNK1 2220/4885 |
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DDT, ACHE, NOTUM | IDH1 1225/4885PTGS2 686/4885MKNK1 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.