SCHEMBL21837111

SCHEMBL21837111

CCSc1c(-c2nc3cc(C(F)(F)F)nnc3n2C)ncn1C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23748059 0.91 — —
SCHEMBL23748074 0.82 POLB (0.30) POLB
SCHEMBL30080527 0.80 — —
SCHEMBL17695958 0.79 POLB (0.33) POLB
SCHEMBL30436972 0.78 POLB (0.31) POLB
SCHEMBL25209584 0.78 POLB (0.31) POLB
SCHEMBL23748081 0.78 PTGS2 (0.36) POLB
Hydrochloric Acid SCHEMBL30080420 0.78 — —
SCHEMBL23971611 0.78 POLB (0.34) POLB
SCHEMBL30177583 0.78 POLB (0.32) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3864015-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES BAYER AG (DE) 2023-05-10 — — EP disclosed
EP-3864015-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES BAYER AG (DE) 2023-05-10 — — EP disclosed
CN-112867713-B Process for preparing imidazole derivatives 拜耳公司 2023-05-05 — — CN disclosed
US-11479565-B2 Process for preparing substituted imidazole derivatives BAYER AKTIENGESELLSCHAFT (DE) 2022-10-25 — — US disclosed
EP-3864016-B1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES BAYER AG (DE) 2022-09-14 — — EP disclosed
US-20220009930-A1 PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2022-01-13 — — US disclosed
US-20210380611-A1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2021-12-09 — — US disclosed
EP-3864015-A1 PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES Bayer Aktiengesellschaft (DE) 2021-08-18 — — EP disclosed
EP-3864016-A1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES Bayer Aktiengesellschaft (DE) 2021-08-18 — — EP disclosed
EP-3636645-A1 PROCESS FOR THE PREPARATION OF SULFUR-SUBSTITUTED PYRIDINE DERIVATIVES Bayer Aktiengesellschaft (DE) 2020-04-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11479565-B2 Process for preparing substituted imidazole derivatives CYP4B1, MAOB, CYP3A4 POLB 56/4885
US-20210380611-A1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES CYP4B1, MAOB, CYP3A4 POLB 56/4885
US-20220009930-A1 PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES UQCRB, CYP3A4, H1-4 POLB 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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