SCHEMBL2183735

SCHEMBL2183735

CCSC1Oc2cc(O)ccc2C=C1c1ccc(O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 12/20 0.41
ESR1 P03372 11/20 0.41
APP P05067 1/20 0.36
PTGS1 P23219 1/20 0.31
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30
YES1 P07947 1/20 0.30
TUBA3C P0DPH7 1/20 0.30
CYP19A1 P11511 1/20 0.30
TUBA1B P68363 1/20 0.30
TUBA4A P68366 1/20 0.30
TUBB4B P68371 1/20 0.30
TUBB3 Q13509 1/20 0.30
TUBB2A Q13885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12413190 0.85 ESR1 (0.41) ESR2ESR1APPPTGS1
SCHEMBL2180799 0.79 ESR1 (0.55) ESR2ESR1APPPTGS1MEN1
SCHEMBL2179974 0.77 ESR1 (0.51) ESR2ESR1APPPTGS1MEN1
SCHEMBL2182335 0.77 ESR1 (0.56) ESR2ESR1APPPTGS1
SCHEMBL2181270 0.76 ESR2 (0.43) ESR2ESR1APPPTGS1MEN1
SCHEMBL2183376 0.75 ESR2 (0.44) ESR2ESR1APPPTGS1
SCHEMBL2183316 0.75 ESR2 (0.48) ESR2ESR1APPPTGS1
SCHEMBL2182963 0.74 ESR1 (0.42) ESR2ESR1APPPTGS1
SCHEMBL13970430 0.74 ESR2 (0.46) ESR2ESR1APPPTGS1MEN1
SCHEMBL2186431 0.73 ESR2 (0.43) ESR2ESR1APPPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120000540-A Light-sensitive whitening and freckle-removing essence and preparation method and application thereof 云南泽希生物科技集团有限公司 2025-05-16 CN claimed
CN-114557945-A Face injection filler for beauty and plastic 上海医妃医药科技有限公司 2022-05-31 CN claimed
CN-120000540-A Light-sensitive whitening and freckle-removing essence and preparation method and application thereof 云南泽希生物科技集团有限公司 2025-05-16 CN disclosed
CN-120000540-A Light-sensitive whitening and freckle-removing essence and preparation method and application thereof 云南泽希生物科技集团有限公司 2025-05-16 CN disclosed
CN-118615241-A Flurbiprofen salt solution and application thereof in anti-inflammatory and analgesic field 吉林化工学院 2024-09-10 CN disclosed
US-20110166142-A1 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES NOVOGEN RESEARCH PTY LIMITED (AU) 2011-07-07 US disclosed
US-20110166142-A1 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES NOVOGEN RESEARCH PTY LIMITED (AU) 2011-07-07 US disclosed
US-20110166142-A1 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES NOVOGEN RESEARCH PTY LIMITED (AU) 2011-07-07 US disclosed
EP-2160385-A1 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES Novogen Research Pty. Ltd. (AU) 2010-03-10 EP disclosed
WO-2009003229-A1 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES NOVOGEN RESEARCH PTY LTD (AU) 2009-01-08 WO disclosed
WO-2009003229-A1 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES NOVOGEN RESEARCH PTY LTD (AU) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166142-A1 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES NFE2L2, PTGS2, PTGES2 ESR2 8/4885ESR1 90/4885APP 2176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.