SCHEMBL2183996

SCHEMBL2183996

C=CN(CCOC(=O)C(=C)C)C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31134670 0.90 THRB (0.35) THRBTSHRALDH1A1TDP1POLB
SCHEMBL3283075 0.80 THRB (0.50) THRBTSHRALDH1A1TDP1POLB
SCHEMBL5360846 0.79 THRB (0.48) THRBTSHRALDH1A1TDP1POLB
Acrylamide SCHEMBL317113 0.77 THRB (0.43) THRBTSHRALDH1A1TDP1POLB
SCHEMBL27901131 0.76 THRB (0.46) THRBTSHRALDH1A1TDP1POLB
Acrylamide SCHEMBL11030958 0.75 THRB (0.42) THRBTSHRALDH1A1TDP1POLB
Acrylamide SCHEMBL11027642 0.74 THRB (0.45) THRBTSHRALDH1A1POLB
SCHEMBL746457 0.74 THRB (0.55) THRBTSHRALDH1A1TDP1POLB
SCHEMBL25435705 0.74 THRB (0.47) THRBTSHRALDH1A1TDP1POLB
Butadiene SCHEMBL29263181 0.74 THRB (0.47) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569623-B1 VINYL-LACTAM-BASED HYDROGEL COATINGS CONSEJO SUPERIOR INVESTIGACION (ES) 2023-08-09 EP claimed
US-11572429-B2 Hydrogels based on vinyl-caprolactam CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) 2023-02-07 US claimed
US-10988591-B2 Vinyl-lactam-based hydrogel coatings CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) 2021-04-27 US claimed
EP-3778675-A1 HYDROGELS BASED ON VINYL CAPROLACTAM Consejo Superior de Investigaciones Cientificas (CSIC) (ES) 2021-02-17 EP claimed
US-20210017316-A1 Hydrogels Based on Vinyl-Caprolactam CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2021-01-21 US claimed
EP-3569623-A1 VINYL-LACTAM-BASED HYDROGEL COATINGS Consejo Superior de Investigaciones Cientificas (CSIC) (ES) 2019-11-20 EP claimed
WO-2019193236-A1 HYDROGELS BASED ON VINYL CAPROLACTAM CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2019-10-10 WO claimed
US-20130011385-A1 TRANSPARENT BACTERIAL CELLULOSE NANOCOMPOSITE HYDROGELS AXCELON BIOPOLYMERS COPRORATION (CA) 2013-01-10 US claimed
WO-2011079380-A1 TRANSPARENT BACTERIAL CELLULOSE NANOCOMPOSITE HYDROGELS AXCELON BIOPOLYMERS CORPORATION (CA) 2011-07-07 WO claimed
US-7279507-B2 Contact lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2007-10-09 US claimed
US-20050148682-A1 Interpenetrating polymer network hydrophilic hydrogels for contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2005-07-07 US claimed
EP-0611367-B1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB (US) 1997-06-25 EP claimed
US-5512205-A BIOMEDICAL ARTICLES, CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1996-04-30 US claimed
US-5449729-A Vinyl monomer and crosslinking agent and acrylates with styrene BAUSCH & LOMB INCORPORATED (US) 1995-09-12 US claimed
EP-0611367-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. BAUSCH & LOMB (US) 1994-08-24 EP claimed
WO-1993009084-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
EP-3569623-B1 VINYL-LACTAM-BASED HYDROGEL COATINGS CONSEJO SUPERIOR INVESTIGACION (ES) 2023-08-09 EP disclosed
US-11572429-B2 Hydrogels based on vinyl-caprolactam CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) 2023-02-07 US disclosed
US-5310779-A Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials BAUSCH & LOMB INCORPORATED (US) 1994-05-10 US disclosed
WO-1993009084-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO disclosed