Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240640 | 0.85 | USP2 (0.44) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL25678641 | 0.83 | USP2 (0.43) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL25678822 | 0.80 | USP2 (0.45) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL15472728 | 0.80 | CYP11B2 (0.41) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL22642600 | 0.79 | USP2 (0.44) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL1966100 | 0.76 | USP2 (0.50) | USP2SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL3612459 | 0.74 | NR1H2 (0.42) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL6114979 | 0.73 | NR1H2 (0.39) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL904136 | 0.72 | USP2 (0.49) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL23797358 | 0.71 | USP2 (0.45) | USP2SMN1; SMN2TSHRALOX15ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768805-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2020-03-25 | — | — | EP | disclosed |