Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29192757 | 0.91 | LMNA (0.59) | TOP1CCR1CCR5CCR8KDM4E | |
| SCHEMBL30837267 | 0.91 | LMNA (0.59) | TOP1CCR1CCR5CCR8KDM4E | |
| SCHEMBL26200013 | 0.90 | TOP1 (0.51) | TOP1CYP19A1CCR1CCR5CCR8 | |
| SCHEMBL26199941 | 0.90 | TOP1 (0.51) | TOP1CYP19A1CCR1CCR5CCR8 | |
| SCHEMBL19762971 | 0.90 | TOP1 (0.51) | TOP1CYP19A1CCR1CCR5CCR8 | |
| SCHEMBL19762930 | 0.90 | TOP1 (0.51) | TOP1CYP19A1CCR1CCR5CCR8 | |
| SCHEMBL19762973 | 0.90 | TOP1 (0.51) | TOP1CYP19A1CCR1CCR5CCR8 | |
| SCHEMBL19762991 | 0.90 | TOP1 (0.51) | TOP1CYP19A1CCR1CCR5CCR8 | |
| SCHEMBL25780004 | 0.90 | TOP1 (0.51) | TOP1CYP19A1CCR1CCR5CCR8 | |
| SCHEMBL30112679 | 0.89 | KDM4E (0.53) | TOP1CYP19A1CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200095224-A1 | NITROGEN HETEROCYCLIC COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2020-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200095224-A1 | NITROGEN HETEROCYCLIC COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS | C5, CCND2, OCIAD2 | TOP1 639/4885CYP19A1 506/4885CCR1 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.