Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | CCR5 | P51681 | 3/20 | 0.53 |
| ▸ | CCR8 | P51685 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112544 | 0.94 | CCR1 (0.47) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL17899337 | 0.93 | CCR1 (0.61) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL16852209 | 0.92 | CCR1 (0.52) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL11962211 | 0.91 | CCR1 (0.64) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL19486732 | 0.91 | MAPT (0.44) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL19486694 | 0.90 | TOP1 (0.48) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL17174057 | 0.90 | KDM4E (0.57) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL30449837 | 0.90 | LMNA (0.61) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL1395123 | 0.90 | LMNA (0.61) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL21841075 | 0.89 | TOP1 (0.53) | KDM4ECCR1CCR5CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107586296-B | Preparation method and application of 2, 9-diaryl substituted phenanthroline and iron complex thereof | 南开大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-110028504-B | Preparation method and application of 2, 9-diaryl substituted o-phenanthroline and cobalt complex thereof | 南开大学（CN） | 2023-01-13 | — | — | CN | disclosed |