Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.60 |
| ▸ | NPY1R | P25929 | 7/20 | 0.60 |
| ▸ | NPY2R | P49146 | 5/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.60 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468898 | 0.93 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5RNTSR2 | |
| SCHEMBL2195052 | 0.91 | NPY4R (0.61) | NPY4RNPY1RNPY2RNPY5RNTSR2 | |
| SCHEMBL2193857 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL30471386 | 0.85 | NPY4R (0.76) | NPY4RNPY1RNPY2RNPY5RNTSR2 | |
| SCHEMBL2190396 | 0.84 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL4672649 | 0.83 | MMP2 (0.48) | — | |
| SCHEMBL4672644 | 0.83 | MMP2 (0.48) | — | |
| SCHEMBL30179204 | 0.83 | NPY4R (0.73) | NPY4RNPY1RNPY2RNPY5RNTSR2 | |
| SCHEMBL31589813 | 0.83 | NPY4R (0.73) | NPY4RNPY1RNPY2RNPY5RNTSR2 | |
| SCHEMBL29354969 | 0.83 | NPY4R (0.67) | NPY4RNPY1RNPY2RNPY5RNTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | NPY4R 567/4885NPY1R 544/4885NPY2R 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.