SCHEMBL16468898

SCHEMBL16468898

CC(C)C[C@@H]([C]=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)N

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.51
NPY1R P25929 10/20 0.51
NPY2R P49146 7/20 0.51
NPY5R Q15761 7/20 0.51
OPRK1 P41145 1/20 0.46
IL1RN P18510 1/20 0.45
ERAP2 Q6P179 1/20 0.45
GHSR Q92847 1/20 0.45
NTSR2 O95665 1/20 0.44
NTSR1 P30989 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2193857 0.96 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL2184229 0.93 NPY4R (0.60) NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL2195052 0.85 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL30575177 0.83 NPY1R (0.56) NPY4RNPY1RNPY2RERAP2GHSR
SCHEMBL27584132 0.81 GHSR (0.53) OPRK1GHSR
SCHEMBL27584126 0.81 GHSR (0.53) OPRK1GHSR
SCHEMBL24473464 0.81 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RNTSR2
SCHEMBL24473382 0.81 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RNTSR2
SCHEMBL24473513 0.81 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RNTSR2
SCHEMBL24473470 0.81 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RNTSR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9173951-B2 Carbohydrate-based drug delivery polymers and conjugates thereof NEKTAR THERAPEUTICS (US) 2015-11-03 US disclosed
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF NEKTAR THERAPEUTICS (US) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF STT3B, STT3A, DDOST NPY4R 2480/4885NPY1R 3329/4885NPY2R 3255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.