Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21242698 | 1.00 | TP53 (0.39) | TP53CA2CA1MMEALDH1A1 | |
| SCHEMBL27391604 | 1.00 | TP53 (0.39) | TP53CA2CA1MMEALDH1A1 | |
| SCHEMBL21242713 | 1.00 | TP53 (0.39) | TP53CA2CA1MMEALDH1A1 | |
| SCHEMBL21844017 | 0.83 | SMN1; SMN2 (0.37) | TP53ALDH1A1 | |
| SCHEMBL24946361 | 0.79 | — | — | |
| SCHEMBL18088383 | 0.76 | ALDH1A1 (0.36) | TP53CA2CA1MMEALDH1A1 | |
| SCHEMBL29858530 | 0.74 | TP53 (0.47) | TP53CA2CA1MMEALDH1A1 | |
| SCHEMBL21621510 | 0.72 | — | — | |
| SCHEMBL14819886 | 0.72 | — | — | |
| SCHEMBL21242710 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590076-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2020-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590076-B2 | Hepatitis B capsid assembly modulators | HAVCR2, COPB1, HDLBP | TP53 385/4885CA2 4777/4885CA1 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.