SCHEMBL218447

SCHEMBL218447

C[C]1C(C)=C(C)c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.37
CDC25A P30304 4/20 0.37
AURKA O14965 1/20 0.37
AURKB Q96GD4 1/20 0.37
TSHR P16473 3/20 0.37
ACHE P22303 2/20 0.37
LMNA P02545 3/20 0.35
ALOX12 P18054 1/20 0.35
S100A4 P26447 3/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
MAP2K7 O14733 2/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
PLIN1 O60240 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 2/20 0.32
MAPT P10636 2/20 0.32
MAOA P21397 2/20 0.32
MAPK1 P28482 2/20 0.32
BLM P54132 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068235 0.87 TSHR (0.47) CDC25BCDC25AAURKAAURKBTSHR
SCHEMBL16684736 0.80 AURKA (0.46) CDC25BCDC25AAURKAAURKBTSHR
SCHEMBL7031478 0.79
SCHEMBL3921115 0.76 MEN1 (0.44) CDC25BCDC25AAURKAAURKBTSHR
SCHEMBL6344310 0.71 FGFR1 (0.36) CDC25BCDC25AAURKAAURKBLMNA
SCHEMBL2965000 0.71 HSD11B1 (0.37) CDC25BCDC25AAURKAAURKBTSHR
SCHEMBL2962651 0.71 AURKA (0.44) CDC25BCDC25AAURKAAURKBTSHR
SCHEMBL15491792 0.71 CDC25B (0.62) CDC25BCDC25AAURKAAURKBLMNA
SCHEMBL8586117 0.69 S100A4 (0.60) CDC25BCDC25AAURKAAURKBLMNA
SCHEMBL4621848 0.69 CDC25A (0.38) CDC25BCDC25AAURKAAURKBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363955-B1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORP (KR) 2008-04-09 EP claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7186783-B2 Process for preparaing partially hydrogenated butadiene polymers KRATON POLYMERS U.S. LLC (US) 2007-03-06 US claimed
US-6943225-B2 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2005-09-13 US claimed
EP-1311561-B1 PROCESS FOR PREPARING PARTIALLY HYDROGENATED BUTADIENE POLYMERS KRATON POLYMERS RES BV (NL) 2005-06-08 EP claimed
WO-2004076502-A1 SUPPORTED MULTINUCLEAR METALLOCENE CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PREPARING THE SAME HONAM PETROCHEMICAL CORPORATION (KR) 2004-09-10 WO claimed
US-20040072677-A1 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2004-04-15 US claimed
US-6683140-B2 Catalyst for polymerization RIKEN (JP) 2004-01-27 US claimed
EP-1363955-A1 MULTINUCLEAR METALLOCENE CATALYST Honam Petrochemical Corporation (KR) 2003-11-26 EP claimed
EP-1311561-A1 PROCESS FOR PREPARING PARTIALLY HYDROGENATED BUTADIENE POLYMERS KRATON Polymers Research B.V. (NL) 2003-05-21 EP claimed
US-20030092851-A1 Process for preparing partially hydrogenated butadiene polymers BANK OF AMERICA, N.A. 2003-05-15 US claimed
WO-2002060964-A1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORPORATION (KR) 2002-08-08 WO claimed
WO-2002034799-A1 PROCESS FOR PREPARING PARTIALLY HYDROGENATED BUTADIENE POLYMERS KRATON POLYMERS RESEARCH B.V. (NL) 2002-05-02 WO claimed
US-5670587-A Catalyst for producing aromatic vinyl compound-based polymer composition and process for producing aromatic vinyl compound-based polymer composition using same IDEMITSU KOSAN CO., LTD. (JP) 1997-09-23 US claimed
EP-3363824-B1 MULTICOMPONENT COPOLYMER, RUBBER COMPOSITION, CROSS-LINKED RUBBER COMPOSITION, RUBBER PRODUCT, AND TIRE BRIDGESTONE CORP (JP) 2024-05-01 EP disclosed
EP-3363831-B1 MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, RUBBER PRODUCT AND TIRE BRIDGESTONE CORP (JP) 2023-02-01 EP disclosed
EP-3363832-B1 MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, RUBBER PRODUCT, AND TIRE BRIDGESTONE CORP (JP) 2023-01-25 EP disclosed
EP-0505890-A2 Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0497207-A2 Process for purification of styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-08-05 EP disclosed
EP-0492282-A1 Process for producing a styrene polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-01 EP disclosed