Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.49 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996867 | 0.82 | PIK3CA (0.54) | TTKPIK3CAPIK3CGHDAC4AKT1 | |
| SCHEMBL26856889 | 0.82 | PIK3CG (0.43) | TTKPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL12068444 | 0.81 | PIK3CA (0.50) | MEN1KMT2ATTKPIK3CAPIK3CG | |
| SCHEMBL1932766 | 0.79 | PIK3CG (0.49) | KMT2ATTKPIK3CAPIK3CGPIK3CD | |
| SCHEMBL936693 | 0.79 | PIK3CG (0.49) | PIK3CAPIK3CGPIK3CDFYNPIK3CB | |
| SCHEMBL26856888 | 0.78 | PIK3CG (0.41) | TTKPIK3CAPIK3CGJAK1PIK3CD | |
| SCHEMBL26856887 | 0.78 | PIK3CG (0.41) | RAB9AMEN1NPC1KMT2APIK3CA | |
| SCHEMBL26856885 | 0.77 | PIK3CG (0.41) | RAB9AMEN1NPC1KMT2APIK3CA | |
| SCHEMBL26856893 | 0.77 | PIK3CG (0.41) | RAB9AMEN1NPC1KMT2APIK3CA | |
| SCHEMBL1931983 | 0.77 | CFTR (0.42) | TTKPIK3CAPIK3CGHDAC4PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676766-B2 | Triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-06-13 | — | — | US | disclosed |
| US-9676766-B2 | Triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-06-13 | — | — | US | disclosed |
| US-9676766-B2 | Triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-06-13 | — | — | US | disclosed |
| EP-2699575-B1 | TRIAZOLOPYRIDINES | BAYER IP GMBH (DE) | 2015-03-25 | — | — | EP | disclosed |
| EP-2699575-B1 | TRIAZOLOPYRIDINES | BAYER IP GMBH (DE) | 2015-03-25 | — | — | EP | disclosed |
| EP-2507235-B1 | TRIAZOLOPYRIMIDINES | BAYER IP GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2507235-B1 | TRIAZOLOPYRIMIDINES | BAYER IP GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| US-20140120087-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-01 | — | — | US | disclosed |
| US-20140120087-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-01 | — | — | US | disclosed |
| EP-2699575-A1 | TRIAZOLOPYRIDINES | Bayer Intellectual Property GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-20120328610-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120328610-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120328610-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-27 | — | — | US | disclosed |
| WO-2012143329-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| EP-2343297-A1 | Triazolopyridines | Bayer Schering Pharma AG (DE) | 2011-07-13 | — | — | EP | disclosed |
| WO-2011063908-A1 | TRIAZOLOPYRIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140120087-A1 | TRIAZOLOPYRIDINES | QDPR, TBXA2R, KCNJ11 | RAB9A 1471/4885MEN1 785/4885NPC1 1075/4885 |
| US-20120328610-A1 | TRIAZOLOPYRIDINES | TTBK1, BUB1, BUB1B | RAB9A 2337/4885MEN1 441/4885NPC1 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.