Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 9/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887257 | 0.87 | KCNH2 (0.42) | SLC10A2PTPN11KCNH2OPRM1 | |
| SCHEMBL21845246 | 0.79 | PTPN11 (0.36) | PTPN11KCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL21940659 | 0.74 | PTPN11 (0.47) | PTPN11KCNH2 | |
| SCHEMBL23046087 | 0.74 | PTPN11 (0.47) | PTPN11KCNH2 | |
| SCHEMBL24388823 | 0.74 | PTPN11 (0.47) | PTPN11KCNH2 | |
| SCHEMBL24091274 | 0.71 | PTPN11 (0.48) | PTPN11KCNH2 | |
| SCHEMBL21940668 | 0.71 | PTPN11 (0.48) | PTPN11KCNH2 | |
| SCHEMBL21940879 | 0.71 | PTPN11 (0.48) | PTPN11KCNH2 | |
| SCHEMBL13085672 | 0.68 | CCR5 (0.49) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL21940878 | 0.67 | SLC6A3 (0.38) | PTPN11KCNH2DRD4OPRM1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061103-A1 | FUSED TRICYCLIC RING DERIVATIVES AS SRC HOMOLOGY-2 PHOSPHATASE INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |