Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.64 |
| ▸ | IGF2R | P11717 | 4/20 | 0.59 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.52 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.52 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.52 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GJA1 | P17302 | 1/20 | 0.45 |
| ▸ | GJB2 | P29033 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143166 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL16249958 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL17993341 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL19860864 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL10174935 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL17904701 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL30891275 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL29602137 | 1.00 | CD209 (0.64) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| Hydrochloric Acid SCHEMBL30891424 | 0.99 | CD209 (0.62) | CD209IGF2RLGALS8LGALS3LGALS4 | |
| SCHEMBL16018775 | 0.96 | CD209 (0.60) | CD209IGF2RLGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220273770-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2022-09-01 | — | — | US | disclosed |
| US-11041009-B2 | Glucose responsive insulin comprising a tri-valent sugar cluster for treatment of diabetes | MERCK SHARP & DOHME CORP. (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200087375-A1 | GLUCOSE RESPONSIVE INSULIN COMPRISING A TRI-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME CORP. (US) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220273770-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | IRS1, GPR119, INSR | CD209 1568/4885IGF2R 5/4885LGALS8 205/4885 |
| US-20200087375-A1 | GLUCOSE RESPONSIVE INSULIN COMPRISING A TRI-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | GPR119, IAPP, INSR | CD209 1476/4885IGF2R 6/4885LGALS8 195/4885 |
| US-11041009-B2 | Glucose responsive insulin comprising a tri-valent sugar cluster for treatment of diabetes | GPR119, IAPP, INSR | CD209 1476/4885IGF2R 6/4885LGALS8 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.