Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.62 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | DUSP22 | Q9NRW4 | 7/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CFTR | P13569 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.52 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184682 | 1.00 | HSPD1 (0.62) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL13236159 | 0.88 | MAPT (0.65) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL2838465 | 0.81 | PTPN2 (0.66) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL2838460 | 0.81 | PTPN2 (0.66) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL2838462 | 0.81 | PTPN2 (0.66) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL14788063 | 0.79 | HSPD1 (0.76) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL13236134 | 0.79 | HSPD1 (0.59) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL20005793 | 0.79 | MEN1 (0.68) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL18103076 | 0.79 | MEN1 (0.68) | HSPD1HSPE1MAPTMEN1KMT2A | |
| SCHEMBL19773079 | 0.77 | CISD1 (0.69) | MAPTMEN1KMT2AATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | HSPD1 3475/4885HSPE1 3159/4885MAPT 4500/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | HSPD1 3475/4885HSPE1 3159/4885MAPT 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.