Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21847376 | 1.00 | MEN1 (0.32) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL21847357 | 1.00 | MEN1 (0.32) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL1404081 | 0.85 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL1619600 | 0.85 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL1403966 | 0.85 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL1404086 | 0.85 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL1403899 | 0.85 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL27696864 | 0.85 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL25433609 | 0.85 | THRA (0.38) | — | |
| SCHEMBL25433406 | 0.85 | THRA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640237-B1 | LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO SIRNA CELL | UNIV HOKKAIDO NAT UNIV CORP (JP) | 2024-02-28 | — | — | EP | disclosed |
| US-20230132645-A1 | LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO SIRNA CELL | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-05-04 | — | — | US | disclosed |
| US-11517528-B2 | Lipid membrane structure for delivery into siRNA cell | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2022-12-06 | — | — | US | disclosed |
| CN-110740985-B | Lipid membrane structures for intracellular delivery of siRNA | 国立大学法人北海道大学 | 2022-08-02 | — | — | CN | disclosed |
| US-20200129431-A1 | LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO siRNA CELL | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2020-04-30 | — | — | US | disclosed |
| EP-3640237-A1 | LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO SIRNA CELL | National University Corporation Hokkaido University (JP) | 2020-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132645-A1 | LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO SIRNA CELL | ABCB4, NPC1L1, LDLR | MEN1 1580/4885KMT2A 1873/4885LMNA 447/4885 |
| US-20200129431-A1 | LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO siRNA CELL | ABCB4, LDLR, NPC1 | MEN1 1759/4885KMT2A 1986/4885LMNA 363/4885 |
| US-11517528-B2 | Lipid membrane structure for delivery into siRNA cell | ABCB4, LDLR, NPC1 | MEN1 1759/4885KMT2A 1986/4885LMNA 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.