Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 4/20 | 0.32 |
| ▸ | CDK19 | Q9BWU1 | 4/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293901 | 1.00 | CHRM2 (0.41) | CHRM2LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL519126 | 0.81 | — | — | |
| SCHEMBL18355718 | 0.77 | LMNA (0.46) | CHRM2LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL22770864 | 0.77 | — | — | |
| SCHEMBL3062964 | 0.75 | LMNA (0.45) | CHRM2LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL25209136 | 0.74 | LMNA (0.42) | CHRM2LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL25239019 | 0.74 | LMNA (0.41) | CHRM2LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL20355472 | 0.74 | LMNA (0.44) | CHRM2LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL341205 | 0.74 | LMNA (0.44) | CHRM2LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL30048976 | 0.74 | LMNA (0.44) | CHRM2LMNAADRA2ACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341777-B1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | NOVABAY PHARMACEUTICALS INC (US) | 2015-01-21 | — | — | EP | disclosed |
| US-8722715-B2 | Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions | NovaBay Pharmaceuticals (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2341777-A1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | NovaBay Pharmaceuticals, Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| US-20100137349-A1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | NOVABAY PHARMACEUTICALS, INC. | 2010-06-03 | — | — | US | disclosed |
| WO-2010054009-A1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | NOVABAY PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137349-A1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | OXA1L, NISCH, ODC1 | CHRM2 4752/4885LMNA 3055/4885ADRA2A 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.