Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.30 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985343 | 0.88 | LRRK2 (0.46) | LRRK2DYRK1A | |
| SCHEMBL21821365 | 0.88 | LRRK2 (0.46) | LRRK2DYRK1A | |
| SCHEMBL16975464 | 0.81 | ALOX15 (0.42) | LRRK2ALOX15 | |
| SCHEMBL21939039 | 0.76 | JAK3 (0.36) | LRRK2DYRK1A | |
| SCHEMBL21938979 | 0.74 | LRRK2 (0.42) | LRRK2DYRK1A | |
| SCHEMBL16975476 | 0.74 | ALOX15 (0.36) | ALOX15 | |
| SCHEMBL21958372 | 0.72 | LRRK2 (0.46) | LRRK2DYRK1A | |
| SCHEMBL21859053 | 0.72 | LRRK2 (0.46) | LRRK2DYRK1A | |
| SCHEMBL16985407 | 0.72 | LRRK2 (0.53) | LRRK2DYRK1A | |
| SCHEMBL16985433 | 0.72 | LRRK2 (0.53) | LRRK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099695-B1 | COMPOUNDS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-04-08 | — | — | EP | disclosed |