Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.42 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21850829 | 0.85 | LMNA (0.43) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL21851152 | 0.81 | DDR1 (0.40) | MELKFGFR1LMNA | |
| SCHEMBL21850877 | 0.73 | LMNA (0.43) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL30329338 | 0.73 | KCNJ1 (0.74) | KCNJ1 | |
| Hydrochloric Acid SCHEMBL27837634 | 0.70 | KDM4E (0.63) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL21850871 | 0.70 | KCNJ1 (0.49) | CHRM2KCNJ1LMNA | |
| SCHEMBL21850860 | 0.69 | SCD (0.40) | CYP1A2KCNJ1LMNACYP2D6 | |
| SCHEMBL22542166 | 0.69 | CYP1A2 (0.62) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL20168449 | 0.69 | KCNJ1 (0.42) | KCNJ1FGFR1PSEN1PSEN2APH1B | |
| SCHEMBL30444963 | 0.69 | KCNJ1 (0.42) | KCNJ1FGFR1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200109135-A1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200109135-A1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | NR0B1, GRK1, GRIN1 | CYP1A2 1414/4885CHRM2 203/4885SLC6A4 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.