SCHEMBL21851237

SCHEMBL21851237

C=CC(=O)N1CCN(C(=O)/C=C\C(=O)O)CC1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
RAB9A P51151 1/20 0.46
KMT2A Q03164 5/20 0.42
TET3 O43151 3/20 0.42
FBXL19 Q6PCT2 3/20 0.42
CXXC5 Q7LFL8 3/20 0.42
KDM2B Q8NHM5 3/20 0.42
CXXC4 Q9H2H0 3/20 0.42
KDM2A Q9Y2K7 3/20 0.42
TET1 Q8NFU7 2/20 0.42
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41
MEN1 O00255 2/20 0.39
POLB P06746 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237862 0.83
SCHEMBL20547259 0.83 TET3 (0.47) ALDH1A1LMNAKMT2ATET3FBXL19
SCHEMBL12764449 0.83 TET3 (0.47) ALDH1A1LMNAKMT2ATET3FBXL19
SCHEMBL167151 0.83 TET3 (0.47) ALDH1A1LMNAKMT2ATET3FBXL19
SCHEMBL12172750 0.81 ALDH1A1 (0.49) ALDH1A1LMNAGAAMAPTKDM4E
SCHEMBL4868093 0.80 POLB (0.56) ALDH1A1LMNAGAAMAPTKDM4E
SCHEMBL12390217 0.80 POLB (0.56) ALDH1A1LMNAGAAMAPTKDM4E
SCHEMBL6651491 0.79 ALDH1A1 (0.47) ALDH1A1LMNAGAAMAPTKDM4E
SCHEMBL4021544 0.79 ALDH1A1 (0.47) ALDH1A1LMNAGAAMAPTKDM4E
SCHEMBL4021537 0.79 ALDH1A1 (0.47) ALDH1A1LMNAGAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020066315-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, LAYERED PRODUCT, PRODUCTION METHOD FOR CURED PRODUCT, AND SEMICONDUCTOR DEVICE 富士フイルム株式会社 2020-04-02 WO disclosed