SCHEMBL2185156

SCHEMBL2185156

CC(=O)OC(C)(C)OC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
TSHR P16473 6/20 0.41
ALDH1A1 P00352 5/20 0.41
LMNA P02545 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
DGAT1 O75907 1/20 0.32
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11351121 0.88 GAA (0.42) GAATSHRALDH1A1LMNA
SCHEMBL5987133 0.86 GAA (0.41) GAATSHRALDH1A1DGAT1
SCHEMBL8915909 0.86 GAA (0.41) GAATSHRALDH1A1LMNAHSD17B10
SCHEMBL298347 0.84
SCHEMBL28427950 0.82
SCHEMBL22504460 0.82
SCHEMBL15159748 0.82 GAA (0.42) GAATSHRALDH1A1DGAT1
SCHEMBL19466200 0.82 GAA (0.42) GAATSHRALDH1A1DGAT1
SCHEMBL15116333 0.82 GAA (0.38) GAATSHRALDH1A1HSD17B10TDP1
SCHEMBL11307977 0.82 ALDH1A1 (0.44) GAATSHRALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3125864-A1 SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS Vasopharm GmbH (DE) 2017-02-08 EP claimed
WO-2015150294-A1 SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS VASOPHARM GMBH (DE) 2015-10-08 WO claimed
CN-103288845-B Spiro-compound 2,4,8,10-tetracarbonyl-3,9-dioxaspiro[5,5] hendecane and synthetic method thereof WUHAN INST TECHNOLOGY 2015-05-20 CN claimed
CN-103274924-B Compound 1,3-dicarboxyl-2,2-bis(carbethoxy)propane and synthesis method thereof WUHAN INSTITUTE OF TECHNOLOGY (CN) 2014-10-15 CN claimed
US-4163116-A REACTING A PHENOL AND AN ESTER CONTAINING COMPOUND GENERAL ELECTRIC COMPANY (US) 1979-07-31 US claimed
EP-2272490-B1 Stabilization of body-care and household products against degradation by UV radiation using merocyanine derivatives BASF SE (DE) 2019-10-16 EP disclosed
US-9617229-B2 Phenylmorpholines and analogues thereof RESEARCH TRIANGLE INSTITUTE (US) 2017-04-11 US disclosed
EP-3125864-A1 SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS Vasopharm GmbH (DE) 2017-02-08 EP disclosed
CN-103333322-B A kind of spirocyclic compound is at the application method of epoxy-resin systems WUHAN INSTITUTE OF TECHNOLOGY (CN) 2016-02-24 CN disclosed
WO-2015150294-A1 SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS VASOPHARM GMBH (DE) 2015-10-08 WO disclosed
CN-103275109-B A kind of compound 1,3-dibrominated magnesium-2,2-bis-(magnesium bromide methyl) propane and preparation method thereof WUHAN INSTITUTE OF TECHNOLOGY (CN) 2015-09-09 CN disclosed
CN-103288845-B Spiro-compound 2,4,8,10-tetracarbonyl-3,9-dioxaspiro[5,5] hendecane and synthetic method thereof WUHAN INST TECHNOLOGY 2015-05-20 CN disclosed
WO-2003047329-A2 METHOD FOR THE PREPARATION OF 6-ALPHA-FLUORO CORTICOSTEROIDS TARO PHARMACEUTICALS U.S.A., INC. (US) 2003-06-12 WO disclosed
CN-1216523-A Process for the production of 1,2-diacetoxy esters EASTMAN CHEM CO (US) 1999-05-12 CN disclosed
CN-1209115-A Process for producing 1, 2-bis (acyloxylesters) EASTMAN CHEM CO (US) 1999-02-24 CN disclosed
US-4876251-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-24 US disclosed
EP-0249909-A1 Tricyclic penam compounds, their production and their use Takeda Chemical Industries, Ltd. (JP) 1987-12-23 EP disclosed
US-4460746-A REACTION WITH INTERPOLYMERS OF ACRYLATE, VINYL ACETATE OR ACRYLONITRILE, UNSATURATED ACID, AND A GLYCIDYL ACRYLATE TH. GOLDSCHMIDT AG (DE) 1984-07-17 US disclosed
US-4172075-A Fluoro-steroids and processes for their manufacture CIBA-GEIGY CORPORATION (US) 1979-10-23 US disclosed
US-4163116-A REACTING A PHENOL AND AN ESTER CONTAINING COMPOUND GENERAL ELECTRIC COMPANY (US) 1979-07-31 US disclosed