SCHEMBL8915909

SCHEMBL8915909

CC(=O)OC(C)(C)OC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
LMNA P02545 2/20 0.35
ALOX15 P16050 2/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21482171 0.89 ALOX15 (0.36) GAALMNAALOX15BLMPMP22
SCHEMBL2185156 0.86 GAA (0.50) GAALMNAALDH1A1TSHRHSD17B10
SCHEMBL11351121 0.76 GAA (0.42) GAALMNAALDH1A1TSHR
SCHEMBL11556994 0.76
SCHEMBL5987133 0.74 GAA (0.41) GAAALDH1A1TSHR
Acetone SCHEMBL6179927 0.72 LMNA (0.39) GAALMNAALOX15BLMPMP22
SCHEMBL298347 0.72
Acetamide SCHEMBL28017647 0.72 LMNA (0.47) GAALMNAALOX15BLMPMP22
SCHEMBL29728523 0.71 ALOX15 (0.36) GAALMNAALOX15BLMPMP22
SCHEMBL28902273 0.71 DGAT1 (0.42) LMNAALOX15BLMPMP22ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1919443-B1 STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS AGAINST DEGRADATION BY UV RADIATION USING MEROCYANINE DERIVATIVES BASF SE (DE) 2020-06-10 EP disclosed
US-5684018-A Acyloxyisopropyl carbamates as prodrugs for amine drugs MERCK & CO., INC. (US) 1997-11-04 US disclosed
WO-1996018605-A1 ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS MERCK & CO., INC. (US) 1996-06-20 WO disclosed