SCHEMBL21851741

SCHEMBL21851741

COC(c1cccc(N)c1)c1n[nH]c2cc(C)nn12

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KRAS P01116 1/20 0.30
SOS1 Q07889 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380104 0.67 KDM4E (0.30)
SCHEMBL14102369 0.66 KDM4E (0.34)
SCHEMBL10908736 0.65 SIGMAR1 (0.40)
SCHEMBL21851731 0.62 KDM4E (0.46)
SCHEMBL21851739 0.62 GFER (0.39)
SCHEMBL29406997 0.61 CYP3A4 (0.48) KRASSOS1
SCHEMBL1841239 0.61 KDM4E (0.39)
SCHEMBL1098188 0.61 CYP3A4 (0.48) KRASSOS1
SCHEMBL25899111 0.60 IDO1 (0.49)
SCHEMBL20852303 0.60 CYP3A4 (0.47) KRASSOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210347964-A1 RESIN COMPOSITION AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2021-11-11 US disclosed
WO-2020071415-A1 RESIN COMPOSITION AND ELECTRONIC DEVICE コニカミノルタ株式会社 2020-04-09 WO disclosed