Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 7/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712832 | 0.76 | CA2 (0.45) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL24858337 | 0.75 | NOS3 (0.56) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL29851068 | 0.75 | NOS3 (0.56) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL20096576 | 0.74 | CA12 (0.38) | CA2HSD17B10PTPN1 | |
| SCHEMBL84522 | 0.73 | PIK3CD (0.40) | PIK3CDCA2CHKAALOX5APFEN1 | |
| SCHEMBL20772336 | 0.72 | PIK3CD (0.42) | PIK3CDCA2CHKAALOX5APFEN1 | |
| SCHEMBL20772327 | 0.71 | PIK3CD (0.41) | PIK3CDCA2CHKAALOX5APFEN1 | |
| SCHEMBL22557297 | 0.71 | PIK3CD (0.49) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL17658887 | 0.71 | NOS3 (0.40) | CA2ALOX5APFEN1NOS3NOS2 | |
| SCHEMBL1440021 | 0.71 | PIK3CD (0.41) | PIK3CDCA2CHKAALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072656-A1 | IMIDOZOPYRIMIDINE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 2020-04-09 | — | — | WO | disclosed |