Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566971 | 0.85 | ADA (0.43) | GPR84CYP19A1ADAKDR | |
| SCHEMBL5334246 | 0.83 | DPP4 (0.43) | DPP4CYP19A1 | |
| SCHEMBL9066952 | 0.80 | CYP19A1 (0.42) | CYP19A1ADAKDR | |
| SCHEMBL18723226 | 0.79 | TBXAS1 (0.35) | DPP4CYP19A1 | |
| SCHEMBL628307 | 0.79 | TBXAS1 (0.42) | DPP4RAD52CYP19A1KDR | |
| SCHEMBL18400707 | 0.77 | LMNA (0.36) | DPP4CYP19A1 | |
| SCHEMBL243704 | 0.77 | TBXAS1 (0.46) | RAD52CYP19A1KDR | |
| SCHEMBL3808952 | 0.77 | DPP4 (0.43) | DPP4CYP19A1 | |
| SCHEMBL20204363 | 0.77 | TBXAS1 (0.46) | RAD52CYP19A1KDR | |
| SCHEMBL11204798 | 0.77 | TBXAS1 (0.46) | RAD52CYP19A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346838-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010040718-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2010-04-15 | — | — | WO | disclosed |