Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CETP | P11597 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | UBE2N | P61088 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433674 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL28433675 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL19132466 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL25266087 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL497548 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL25193896 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL11121661 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL11115743 | 1.00 | GPR84 (0.59) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL3178801 | 0.98 | GPR84 (0.57) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL28032356 | 0.98 | GPR84 (0.57) | GPR84SPHK1FFAR1CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630795-B1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | ENZYMASTER NINGBO BIO ENG CO LTD (CN) | 2023-07-26 | — | — | EP | disclosed |
| EP-3630795-B1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | ENZYMASTER NINGBO BIO ENG CO LTD (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-110869383-B | Engineered polypeptides and their use in the synthesis of beta-hydroxy-alpha-amino acids | 宁波酶赛生物工程有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-110914288-B | Engineered aldolase polypeptides and uses thereof | 宁波酶赛生物工程有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-11512303-B2 | Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
| EP-3630798-B1 | ENGINEERED ALDOLASE POLYPEPTIDES AND THEIR APPLICATIONS IN SYNTHESIS OF BETA-HYDROXY-ALPHA-AMINO ACIDS | ENZYMASTER NINGBO BIO ENG CO LTD (CN) | 2022-11-23 | — | — | EP | disclosed |
| US-11274287-B2 | Engineered aldolase polypeptides and uses thereof | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2022-03-15 | — | — | US | disclosed |
| US-20210284987-A1 | ENGINEERED POLYPEPTIDES AND THEIR APPLICATIONS IN THE SYNTHESIS OF BETA-HYDROXY-ALPHA-AMINO ACIDS | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2021-09-16 | — | — | US | disclosed |
| US-20200123525-A1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2020-04-23 | — | — | US | disclosed |
| US-20200123525-A1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2020-04-23 | — | — | US | disclosed |
| CN-110914288-A | Engineered aldolase polypeptide and application thereof | 宁波酶赛生物工程有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-110869383-A | Engineered polypeptide and application thereof in synthesis of β -hydroxy- α -amino acid | 宁波酶赛生物工程有限公司 | 2020-03-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274287-B2 | Engineered aldolase polypeptides and uses thereof | DERA, ALDOA, TKT | GPR84 2471/4885SPHK1 3032/4885FFAR1 2607/4885 |
| US-20200123525-A1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | DERA, ALDOA, TKT | GPR84 2471/4885SPHK1 3032/4885FFAR1 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.