Sugi Predict

Sugi Predict / Compounds / SCHEMBL497548

SCHEMBL497548

SCHEMBL497548

CCCCCCCCCCCCCCCC(O)C(N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR84 Q9NQS5 7/20 0.59
▸ SPHK1 Q9NYA1 2/20 0.59
▸ FFAR1 O14842 1/20 0.59
▸ CYP2D6 P10635 2/20 0.55
▸ MAPT P10636 2/20 0.55
▸ GMNN O75496 1/20 0.55
▸ LMNA P02545 1/20 0.55
▸ POLB P06746 1/20 0.55
▸ THPO P40225 1/20 0.55
▸ MTOR P42345 1/20 0.55
▸ BLM P54132 1/20 0.55
▸ KDM4E B2RXH2 1/20 0.55
▸ TP53 P04637 1/20 0.55
▸ CYP1A2 P05177 1/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ CETP P11597 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ UBE2N P61088 1/20 0.55
▸ GRIK1 P39086 2/20 0.53
▸ GRIK2 Q13002 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28433674 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL21853754 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL28433675 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL19132466 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL25266087 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL25193896 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL11121661 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL11115743 1.00 GPR84 (0.59) GPR84SPHK1FFAR1CYP2D6MAPT
Hydrochloric Acid SCHEMBL3178801 0.98 GPR84 (0.57) GPR84SPHK1FFAR1CYP2D6MAPT
SCHEMBL28032356 0.98 GPR84 (0.57) GPR84SPHK1FFAR1CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6797347-B2 INORGANIC PIGMENT THAT HAS BEEN MODIFIED TO HAVE A POSITIVE CHARGE COMPLEX COMPRISING A METAL ION AND AN ORGANIC LIGAND HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-09-28 — — US claimed
US-20030048346-A1 Pigment treatment in paper coating compositions for improving ink-jet printing performance RENESAS TECHNOLOGY CORP. (JP) 2003-03-13 — — US claimed
US-6505929-B1 Organic pigment in the paper is modified by a metal-charge complex which causes anionic colorants to be precipitated on paper surface; improved resolution, color retention, water-fastness, smearfastness, image retention, density HEWLETT-PACKARD COMPANY 2003-01-14 — — US claimed
US-6204006-B1 TREATING PARENT STRAIN OF YEAST WHICH NATURALLY PRODUCES TETRAACETYLPHYTOSPHINGOSINE WITH A MUTAGEN AND SELECTING HIGH YIELD MUTANT STRAIN; FOR PRODUCTION OF AT LEAST 0.030 GRAMS PER YEAST DRY WEIGHT FROM SHAKING, LIQUID CULTURE DSM, N.V. (NL) 2001-03-20 — — US claimed
EP-0827842-B1 Pigment treatment in paper coating compositions for improving ink-jet printing performance HEWLETT PACKARD CO (US) 2000-04-19 — — EP claimed
EP-0827842-A1 Pigment treatment in paper coating compositions for improving ink-jet printing performance Hewlett-Packard Company (US) 1998-03-11 — — EP claimed
US-4851316-A Liquid toner compositions with amino acids and polyvalent metal complexes as charge control additives XEROX CORPORATION (US) 1989-07-25 — — US claimed
CN-105051051-B Method for synthesizing sphingomyelin and dihydrosphingomyelin 萨瑞斯治疗控股公司 2021-07-16 — — CN disclosed
EP-3842443-A1 METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS Cerenis Therapeutics Holding SA (FR) 2021-06-30 — — EP disclosed
EP-3363805-B1 METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS CERENIS THERAPEUTICS HOLDING SA (FR) 2020-12-16 — — EP disclosed
US-20190345190-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. 2019-11-14 — — US disclosed
US-20190315785-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. 2019-10-17 — — US disclosed
EP-3363805-A1 METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS Cerenis Therapeutics Holding SA (FR) 2018-08-22 — — EP disclosed
WO-1996026933-A1 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES GILEAD SCIENCES, INC. (US) 1996-09-06 — — WO disclosed
EP-0726960-A1 MICROBIAL STRAINS PRODUCING SPHINGOLIPID BASES GIST-BROCADES N.V. (NL) 1996-08-21 — — EP disclosed
WO-1996023801-A2 NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME GILEAD SCIENCES, INC. (US) 1996-08-08 — — WO disclosed
EP-0719273-A1 NUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1996-07-03 — — EP disclosed
WO-1995012683-A1 MICROBIAL STRAINS PRODUCING SPHINGOLIPID BASES GIST-BROCADES N.V. (NL) 1995-05-11 — — WO disclosed
WO-1995007920-A1 NUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1995-03-23 — — WO disclosed
US-4851316-A Liquid toner compositions with amino acids and polyvalent metal complexes as charge control additives XEROX CORPORATION (US) 1989-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315785-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS PIK3CA, TYMP, ITPA GPR84 4191/4885SPHK1 1491/4885FFAR1 4691/4885
US-20190345190-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS PIK3CA, TYMP, ITPA GPR84 4191/4885SPHK1 1491/4885FFAR1 4691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.