Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 4/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.46 |
| ▸ | GRM6 | O15303 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25875906 | 1.00 | ACP3 (0.48) | ACP3L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL21853776 | 1.00 | ACP3 (0.48) | ACP3L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL21853774 | 1.00 | ACP3 (0.48) | ACP3L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL9160028 | 0.82 | ALDH1A1 (0.62) | L3MBTL1MEN1HPGDKMT2AGRM8 | |
| SCHEMBL1067934 | 0.77 | ACP3 (0.50) | ACP3L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL3109358 | 0.77 | AOC3 (0.52) | L3MBTL1HPGDSMN1; SMN2LMNACES2 | |
| SCHEMBL3109355 | 0.77 | AOC3 (0.52) | L3MBTL1HPGDSMN1; SMN2LMNACES2 | |
| SCHEMBL1104876 | 0.76 | TSHR (0.52) | ACP3L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL22301338 | 0.75 | ACP3 (0.51) | ACP3L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL27459231 | 0.75 | ACP3 (0.48) | ACP3L3MBTL1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274287-B2 | Engineered aldolase polypeptides and uses thereof | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2022-03-15 | — | — | US | disclosed |
| US-20200123525-A1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2020-04-23 | — | — | US | disclosed |
| CN-110914288-A | Engineered aldolase polypeptide and application thereof | 宁波酶赛生物工程有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-110869383-A | Engineered polypeptide and application thereof in synthesis of β -hydroxy- α -amino acid | 宁波酶赛生物工程有限公司 | 2020-03-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274287-B2 | Engineered aldolase polypeptides and uses thereof | DERA, ALDOA, TKT | ACP3 1149/4885L3MBTL1 1339/4885MEN1 4563/4885 |
| US-20200123525-A1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | DERA, ALDOA, TKT | ACP3 1149/4885L3MBTL1 1339/4885MEN1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.