Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109358 | 1.00 | AOC3 (0.52) | AOC3CYP2C19CYP2D6CYP1A2LMNA | |
| Trifluoroacetic Acid SCHEMBL27681692 | 0.83 | AOC3 (0.44) | AOC3CYP2C19CYP2D6CYP1A2LMNA | |
| SCHEMBL60356 | 0.81 | AOC3 (0.57) | AOC3CYP2D6LMNACES2CES1 | |
| SCHEMBL9683893 | 0.81 | AOC3 (0.57) | AOC3CYP2D6LMNACES2CES1 | |
| SCHEMBL5940495 | 0.80 | CYP2D6 (0.48) | AOC3CYP2C19CYP2D6CYP1A2LMNA | |
| SCHEMBL5860575 | 0.80 | LMNA (0.48) | AOC3CYP2C19CYP2D6LMNACES2 | |
| SCHEMBL8496310 | 0.80 | CYP2D6 (0.48) | AOC3CYP2C19CYP2D6CYP1A2LMNA | |
| SCHEMBL29833611 | 0.79 | LMNA (0.47) | AOC3CYP2C19CYP2D6CYP1A2LMNA | |
| SCHEMBL2996171 | 0.79 | GRM4 (0.43) | LMNA | |
| SCHEMBL411887 | 0.79 | AOC3 (0.59) | AOC3LMNAHIF1AADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7327688-A | — | — | None | — | — | JP | disclosed |
| EP-2239335-B1 | PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS | AJINOMOTO KK (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-8372607-B2 | Method for producing serine derivative and protein used for the same | AJINOMOTO CO., INC. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-20100317068-A1 | METHOD FOR PRODUCING SERINE DERIVATIVE AND PROTEIN USED FOR THE SAME | AJINOMOTO CO., INC. (JP) | 2010-12-16 | — | — | US | disclosed |
| EP-2239335-A1 | PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS | Ajinomoto Co., Inc. (JP) | 2010-10-13 | — | — | EP | disclosed |
| EP-0507153-B1 | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids | CELGENE CORP (US) | 1997-07-09 | — | — | EP | disclosed |
| JP-H07327688-A | PRODUCTION OF ALPHA-METHYL-BETA-HYDROXYPHENYLALANINE OR ITS DERIVATIVE | AJINOMOTO CO INC | 1995-12-19 | — | — | JP | disclosed |
| US-5346828-A | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase | CELGENE CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0507153-A2 | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids | CELGENE CORPORATION (US) | 1992-10-07 | — | — | EP | disclosed |
| US-3998955-A | 2-CARBOXY OR 2-ALKOXYCARBONYL-PYRIDINES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317068-A1 | METHOD FOR PRODUCING SERINE DERIVATIVE AND PROTEIN USED FOR THE SAME | SPR, AMD1, DAO | AOC3 3222/4885CYP2C19 3486/4885CYP2D6 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.