Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707997 | 0.88 | NPSR1 (0.49) | HTR2CNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL3017853 | 0.87 | HTR2C (0.52) | HTR2CNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL6487292 | 0.87 | HTR2C (0.52) | HTR2CNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL6501753 | 0.87 | HTR2C (0.52) | HTR2CNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL1257136 | 0.87 | HTR2C (0.50) | HTR2CNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL7251746 | 0.87 | HTR2C (0.53) | HTR2CNPSR1TSHRL3MBTL1CTRB1 | |
| SCHEMBL8220722 | 0.87 | HTR2C (0.53) | HTR2CNPSR1TSHRL3MBTL1CTRB1 | |
| Hydrochloric Acid SCHEMBL7013165 | 0.86 | HTR2C (0.51) | HTR2CNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL4674934 | 0.85 | HTR2C (0.52) | HTR2CNPSR1CTRB1PREPNPC1 | |
| SCHEMBL12479521 | 0.84 | SMN1; SMN2 (0.53) | HTR2CNPSR1TSHRL3MBTL1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081917-A1 | ΒETA-CATENIN AND B-CELL LYMPHOMA 9 (BCL9) INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |