Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21854732 | 0.88 | HTR2C (0.51) | NPSR1TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL3017853 | 0.84 | HTR2C (0.52) | NPSR1TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL13958801 | 0.84 | NPSR1 (0.66) | NPSR1TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL6501753 | 0.84 | HTR2C (0.52) | NPSR1TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL6487292 | 0.84 | HTR2C (0.52) | NPSR1TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL1257136 | 0.84 | HTR2C (0.50) | NPSR1TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL7251746 | 0.84 | HTR2C (0.53) | NPSR1TSHRHTR2CL3MBTL1CTRB1 | |
| SCHEMBL8220722 | 0.84 | HTR2C (0.53) | NPSR1TSHRHTR2CL3MBTL1CTRB1 | |
| SCHEMBL3788946 | 0.83 | HTR2C (0.49) | NPSR1TSHRHTR2CL3MBTL1FKBP1A | |
| Trifluoroacetic Acid SCHEMBL21854853 | 0.83 | HTR2C (0.47) | NPSR1TSHRKDM4ELMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747490-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1998-05-05 | — | — | US | disclosed |