SCHEMBL218558

SCHEMBL218558

C=CCC(C=C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 1/20 0.42
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTR2A P28223 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
CYP3A4 P08684 1/20 0.34
TSHR P16473 2/20 0.34
HRH1 P35367 1/20 0.33
MTOR P42345 1/20 0.33
RAB9A P51151 1/20 0.33
GRM7 Q14831 1/20 0.33
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402837 0.83 CYP2C19 (0.53) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL17616784 0.83 CYP2C19 (0.44) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL2319050 0.83 CYP2C19 (0.44) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL29232062 0.82 CYP2C19 (0.38) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL7983050 0.79 CYP2C19 (0.38) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL19614981 0.79 CYP2C19 (0.46) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL7983048 0.79 CYP2C19 (0.38) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL11421389 0.79 CYP2C19 (0.50) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL6016109 0.79 CYP2C19 (0.39) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL9617749 0.78 ESR1 (0.39) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584332-A1 LOW DIELECTRIC LOSS THERMOSETTING RESIN COMPOSITION Polyscope Polymers B.V. (NL) 2025-07-16 EP claimed
WO-2024052838-A1 LOW DIELECTRIC LOSS THERMOSETTING RESIN COMPOSITION POLYSCOPE POLYMERS B.V. (NL) 2024-03-14 WO claimed
EP-4335902-A1 LOW DIELECTRIC LOSS THERMOSETTING RESIN COMPOSITION Polyscope Polymers B.V. (NL) 2024-03-13 EP claimed
US-12637604-B2 Silicon-containing thermally conductive pastes WACKER CHEMIE AG (DE) 2026-05-26 US disclosed
EP-4584332-A1 LOW DIELECTRIC LOSS THERMOSETTING RESIN COMPOSITION Polyscope Polymers B.V. (NL) 2025-07-16 EP disclosed
US-12290981-B2 3D printing apparatus for layer-by-layer fabrication of objects using layer transfer printing WACKER CHEMIE AG (DE) 2025-05-06 US disclosed
US-20250019585-A1 ALUMINUM-CONTAINING THERMAL PASTES WACKER CHEMIE AG (DE) 2025-01-16 US disclosed
US-20240417582-A1 ELECTRICALLY CONDUCTIVE SILICONE COMPOSITION WITH CARBON NANOTUBES AND CARBON BLACK WACKER CHEMIE AG (DE) 2024-12-19 US disclosed
US-20240399021-A1 ANTIMICROBIAL COMPOSITION AND METHOD FOR MAKING THE SAME WACKER CHEMIE AG (DE) 2024-12-05 US disclosed
US-20240309258-A1 SILICON-CONTAINING THERMALLY CONDUCTIVE PASTES WACKER CHEMIE AG (DE) 2024-09-19 US disclosed
CN-118102877-A Antimicrobial compositions and methods of making the same 瓦克化学股份公司 2024-05-28 CN disclosed
US-6187890-B1 CROSSLINK BY REACTION OF ALIPHATICALLY UNSATURATED GROUPS WITH SI-BONDED HYDROGEN (HYDROSILYLATION) IN THE PRESENCE OF A CATALYST, TYPICALLY A PLATINUM COMPOUND WACKER-CHEMIE GMBH (DE) 2001-02-13 US disclosed
EP-0982370-B1 Curable polysiloxane compositions WACKER CHEMIE GMBH (DE) 2000-12-20 EP disclosed
EP-0994159-A1 Curable organopolysiloxane composition Wacker-Chemie GmbH (DE) 2000-04-19 EP disclosed
EP-0982370-A1 Curable polysiloxane compositions Wacker-Chemie GmbH (DE) 2000-03-01 EP disclosed
EP-0924166-A1 THERMOPLASTIC-COATED AMMONIUM POLYPHOSPHATE AND PROCESS FOR THE PREPARATION THEREOF CHISSO CORPORATION (JP) 1999-06-23 EP disclosed
US-4784784-A ESTERS OF POLYOXYETHYLENE GLYCOL MODIFIED WITH POLYALKYLENE PENNZOIL PRODUCTS COMPANY (US) 1988-11-15 US disclosed
EP-0253668-A1 Succinic acid esters and hydraulic fluids therefrom PENNZOIL PRODUCTS COMPANY (US) 1988-01-20 EP disclosed
US-4689166-A Succinic acid esters and hydraulic fluids thereform PENNZOIL PRODUCT COMPANY (US) 1987-08-25 US disclosed
US-4450281-A Process for the preparation of a polyalkenyl succinic anhydride CHEVRON RESEARCH COMPANY (US) 1984-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240399021-A1 ANTIMICROBIAL COMPOSITION AND METHOD FOR MAKING THE SAME DDOST, NACA, CD68 CYP2C19 2774/4885SMN1; SMN2 2615/4885ALDH1A1 3742/4885
US-12637604-B2 Silicon-containing thermally conductive pastes SAMM50, PIEZO1, SIK1 CYP2C19 3187/4885SMN1; SMN2 370/4885ALDH1A1 4434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.