Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319050 | 1.00 | CYP2C19 (0.44) | CYP2C19SMN1; SMN2CYP2D6KDM4EMAPT | |
| Ethylene SCHEMBL9347773 | 0.83 | LMNA (0.34) | CYP2C19KDM4EMAPTALOX15CYP3A4 | |
| SCHEMBL218558 | 0.83 | CYP2C19 (0.52) | CYP2C19SMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL6817626 | 0.83 | CYP2D6 (0.39) | CYP2C19CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL17615170 | 0.79 | CYP2C19 (0.37) | CYP2C19SMN1; SMN2CYP2D6KDM4EHTR2A | |
| Citronellal SCHEMBL2419804 | 0.78 | ALOX15 (0.36) | CYP2C19KDM4EALOX15ALDH1A1LMNA | |
| SCHEMBL7983050 | 0.76 | CYP2C19 (0.38) | CYP2C19SMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL7983048 | 0.76 | CYP2C19 (0.38) | CYP2C19SMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL2452392 | 0.76 | CYP2C19 (0.44) | CYP2C19SMN1; SMN2CYP2D6KDM4EALDH1A1 | |
| SCHEMBL6016109 | 0.76 | CYP2C19 (0.39) | CYP2C19SMN1; SMN2KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | ALDH1A1, ALDH3A1, ADH1A | CYP2C19 770/4885SMN1; SMN2 3572/4885CYP2D6 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.