Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188348 | 0.84 | KMT2A (0.42) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2188423 | 0.82 | CSNK1E (0.56) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2189135 | 0.81 | LMNA (0.42) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2188767 | 0.78 | LMNA (0.62) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2185579 | 0.78 | LMNA (0.48) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2187340 | 0.78 | LMNA (0.57) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2187871 | 0.75 | LMNA (0.54) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2188562 | 0.74 | LMNA (0.67) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2192333 | 0.74 | LMNA (0.53) | LMNATSHRMEN1MAPK1KMT2A | |
| SCHEMBL2187357 | 0.72 | LMNA (0.57) | LMNATSHRMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |