Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810535 | 0.91 | DHODH (1.00) | DHODHALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2186715 | 0.86 | DHODH (0.63) | DHODHALDH1A1CYP3A4CYP2C9ALOX12 | |
| SCHEMBL2185804 | 0.80 | KMT2A (0.59) | DHODHMEN1KMT2ATP53HTT | |
| SCHEMBL11344615 | 0.79 | NAMPT (0.68) | DHODHALDH1A1CYP3A4CYP2C9ALOX12 | |
| SCHEMBL20963276 | 0.79 | MEN1 (0.59) | DHODHALDH1A1CYP3A4CYP2C9ALOX12 | |
| SCHEMBL1124226 | 0.78 | DHODH (0.78) | DHODHALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19011349 | 0.77 | DHODH (0.55) | DHODHALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31611995 | 0.76 | DHODH (0.75) | DHODHALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1703428 | 0.76 | DHODH (0.51) | DHODHHPGDMEN1KMT2ALMNA | |
| SCHEMBL1389175 | 0.76 | PKM (0.74) | ALDH1A1HPGDMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |