Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761817 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| SCHEMBL18114152 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| SCHEMBL21858616 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| SCHEMBL4762312 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| SCHEMBL21858733 | 0.75 | PIK3CD (0.52) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| SCHEMBL18114129 | 0.73 | PIK3CD (0.47) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| Hydrochloric Acid SCHEMBL20378314 | 0.73 | PIK3CD (0.43) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| SCHEMBL4419714 | 0.71 | TSHR (0.41) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| Hydrochloric Acid SCHEMBL21858794 | 0.69 | PIK3CD (0.40) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD | |
| SCHEMBL19128679 | 0.69 | PIK3CD (0.60) | ALDH1A1TSHRHPGDSMN1; SMN2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355106-A1 | NEW AMINO-PYRIMIDONYL-PIPERIDINYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2021-11-18 | — | — | US | disclosed |
| CN-113038990-A | Novel amino-pyrimidinone-piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-06-25 | — | — | CN | disclosed |
| WO-2020079205-A1 | NEW AMINO-PYRIMIDONYL-PIPERIDINYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355106-A1 | NEW AMINO-PYRIMIDONYL-PIPERIDINYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | QDPR, QARS1, QPCTL | ALDH1A1 1957/4885TSHR 1434/4885HPGD 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.