SCHEMBL2185946

SCHEMBL2185946

CCC(C)OP(=O)(O)OC(C)CC.[Zn]

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 3/20 0.37
MMP1 P03956 2/20 0.35
MMP2 P08253 2/20 0.35
METAP1 P53582 1/20 0.35
MMP3 P08254 1/20 0.35
SMPD1 P17405 3/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP8 P22894 1/20 0.32
CA9 Q16790 1/20 0.32
FDPS P14324 4/20 0.32
TSHR P16473 1/20 0.30
ANPEP P15144 4/20 0.30
ERAP1 Q9NZ08 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497286 0.97 LAP3 (0.39) LAP3MMP1MMP2METAP1MMP3
SCHEMBL11410937 0.91 CTSA (0.37) LAP3MMP1MMP2METAP1MMP3
SCHEMBL6014564 0.87 LAP3 (0.41) LAP3METAP1FDPSANPEPERAP1
SCHEMBL13557334 0.86 MMP1 (0.38) LAP3MMP1MMP2METAP1MMP3
SCHEMBL11409309 0.84 PPARD (0.39) LAP3MMP1MMP2METAP1MMP3
SCHEMBL2863833 0.84 BTN3A1 (0.38) LAP3METAP1SMPD1FDPS
SCHEMBL485995 0.82
Sulfotep SCHEMBL10437268 0.82 PPARD (0.35) TSHR
SCHEMBL27818853 0.81 METAP1 (0.47) LAP3METAP1SMPD1FDPS
SCHEMBL13147013 0.81 LAP3 (0.31) LAP3MMP1MMP2METAP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2497819-B1 Lubricant composition JX NIPPON OIL & ENERGY CORP (JP) 2017-01-04 EP disclosed
EP-2497820-B1 Lubricant composition JX NIPPON OIL & ENERGY CORP (JP) 2016-06-29 EP disclosed
CN-102177227-B Lubricant composition and method for producing same JX NIPPON OIL & ENERGY CORP 2013-12-18 CN disclosed
US-8563486-B2 Lubricant composition and method for producing same JX NIPPON OIL & ENERGY CORPORATION (JP) 2013-10-22 US disclosed
EP-2497820-A1 Lubricant composition and method for producing same JX Nippon Oil & Energy Corporation (JP) 2012-09-12 EP disclosed
EP-2497819-A1 Lubricant composition and method for producing same JX Nippon Oil & Energy Corporation (JP) 2012-09-12 EP disclosed
US-20110218131-A1 LUBRICANT COMPOSITION AND METHOD FOR PRODUCING SAME JX NIPPON OIL & ENERGY CORPORATION (JP) 2011-09-08 US disclosed
EP-2343357-A1 LUBRICANT COMPOSITION AND METHOD FOR PRODUCING SAME JX Nippon Oil & Energy Corporation (JP) 2011-07-13 EP disclosed