SCHEMBL218597

SCHEMBL218597

CCCCC(C)Nc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
HSD17B10 Q99714 6/20 0.62
ALOX15 P16050 4/20 0.62
TSHR P16473 4/20 0.62
ALOX12 P18054 4/20 0.62
CYP3A4 P08684 3/20 0.62
MAPK1 P28482 3/20 0.62
HIF1A Q16665 2/20 0.62
TDP1 Q9NUW8 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
THRB P10828 2/20 0.56
LMNA P02545 2/20 0.56
RECQL P46063 1/20 0.56
ATM Q13315 1/20 0.56
MAPT P10636 5/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TP53 P04637 1/20 0.47
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1662136 0.95 ALDH1A1 (0.60) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL809566 0.93 ALDH1A1 (0.58) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL38948 0.93 ALDH1A1 (0.58) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL809646 0.93 ALDH1A1 (0.58) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL11353374 0.93 ALDH1A1 (0.58) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL1453959 0.93 ALDH1A1 (0.50) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL18660176 0.89 ALDH1A1 (0.66) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL18660185 0.89 ALDH1A1 (0.66) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL1846955 0.89 ALDH1A1 (0.66) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL18660180 0.89 ALDH1A1 (0.66) ALDH1A1HSD17B10ALOX15TSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8313542-B2 Antioxidant additive for biodiesel fuels CHEMTURA CORPORATION (US) 2012-11-20 US claimed
EP-2029704-B1 ANTIOXIDANT ADDITIVE FOR BIODIESEL FUELS CHEMTURA CORP (US) 2012-08-01 EP claimed
US-8062551-B2 Antiozonant blends CHEMTURA CORPORATION (US) 2011-11-22 US claimed
EP-2013273-B1 ANTIOZONANT BLENDS CHEMTURA CORP (US) 2011-11-16 EP claimed
WO-2011130994-A1 MULTI-USER CHANNEL ESTIMATION METHOD AND DEVICE 中兴通讯股份有限公司 (CN) 2011-10-27 WO claimed
US-20110209390-A1 Antioxidant Additive for Biodiesel Fuels LANXESS SOLUTIONS US INC. 2011-09-01 US claimed
US-7964002-B2 Antioxidant additive for biodiesel fuels CHEMTURA CORPORATION (US) 2011-06-21 US claimed
EP-1976821-B1 DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE CHEMTURA CORP (US) 2011-05-25 EP claimed
JP-2009540100-A 2009-11-19 JP claimed
EP-2029704-A1 ANTIOXIDANT ADDITIVE FOR BIODIESEL FUELS CHEMTURA CORPORATION (US) 2009-03-04 EP claimed
WO-2007145738-A1 ANTIOXIDANT ADDITIVE FOR BIODIESEL FUELS CHEMTURA CORPORATION (US) 2007-12-21 WO claimed
US-20070289203-A1 Synergistic blend of an aromatic diamine and sterically hindered phenol as fuel additive for biodiesel fatty esters LANXESS SOLUTIONS US INC. 2007-12-20 US claimed
WO-2007130262-A1 ANTIOZONANT BLENDS CHEMTURA CORPORATION (US) 2007-11-15 WO claimed
US-20070260000-A1 Antiozonant blends ADDIVANT USA, LLC 2007-11-08 US claimed
US-20070173668-A1 Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine LANXESS SOLUTIONS US INC. 2007-07-26 US claimed
WO-2004094572-A2 COMBINATIONS OF ANTI-OXIDANTS AND BIOCIDES IN METAL WORKING FLUIDS CHEMTURA CORPORATION (US) 2004-11-04 WO claimed
US-20040204326-A1 Anti-oxidants in soluble oil base for metal working fluids CROMPTON CORPORATION 2004-10-14 US claimed
US-6103674-A Oil-soluble molybdenum multifunctional friction modifier additives for lubricant compositions UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-08-15 US claimed
US-5128022-A Inhibition of fouling and polymerization BETZ LABORATORIES, INC. (US) 1992-07-07 US claimed
US-5068438-A Granulation and rotation with heat treatment to form free-flowing particles MITSUBISHI MONSANTO CHEMICAL COMPANY (JP) 1991-11-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173668-A1 Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine PNMT, AAAS, PNN ALDH1A1 663/4885HSD17B10 2077/4885ALOX15 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.