Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910803 | 0.98 | MCHR1 (0.42) | MCHR1HTR7CDK9DYRK1ADYRK2 | |
| SCHEMBL10911295 | 0.89 | MCHR1 (0.44) | MCHR1HTR7CDK9DYRK1ADYRK2 | |
| SCHEMBL27852278 | 0.87 | MCHR1 (0.45) | MCHR1HTR7CDK9DYRK1ADYRK2 | |
| SCHEMBL27852180 | 0.86 | MCHR1 (0.47) | MCHR1HTR7CDK9DYRK1ADYRK2 | |
| SCHEMBL7520131 | 0.86 | MCHR1 (0.47) | MCHR1HTR7CDK9DYRK1ADYRK2 | |
| SCHEMBL2521218 | 0.84 | HTR7 (0.47) | MCHR1HTR7ALDH1A1LMNAMAPT | |
| SCHEMBL30271358 | 0.82 | MAPK8 (0.49) | HTR7CDK9DYRK1ADYRK2ALDH1A1 | |
| SCHEMBL1671304 | 0.82 | MAPK8 (0.49) | HTR7CDK9DYRK1ADYRK2ALDH1A1 | |
| SCHEMBL30328346 | 0.81 | TSHR (0.41) | HTR7CDK9DYRK1ADYRK2ALDH1A1 | |
| SCHEMBL17980783 | 0.81 | TSHR (0.41) | HTR7CDK9DYRK1ADYRK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008487-B2 | Substituted thieno[2,3-D]pyrimidines as fungicides | DOW AGROSCIENCES LLC (US) | 2011-08-30 | — | — | US | disclosed |
| EP-1802632-B1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2011-07-13 | — | — | EP | disclosed |
| US-20060089370-A1 | Thieno-pyrimidine compounds having fungicidal activity | BREWSTER WILLIAM K | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089370-A1 | Thieno-pyrimidine compounds having fungicidal activity | TYMP, DPM1, TYMS | MCHR1 4515/4885HTR7 2157/4885CDK9 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.