Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852180 | 1.00 | MCHR1 (0.47) | MCHR1TSHRSOAT1KCNH2TLR8 | |
| SCHEMBL27852278 | 0.98 | MCHR1 (0.45) | MCHR1TSHRSOAT1KCNH2TLR8 | |
| SCHEMBL10911295 | 0.93 | MCHR1 (0.44) | MCHR1TSHRKCNH2TLR8CDK9 | |
| SCHEMBL10910803 | 0.87 | MCHR1 (0.42) | MCHR1TSHRTLR8CDK9DYRK1A | |
| SCHEMBL8583652 | 0.87 | SOAT1 (0.51) | MCHR1TSHRSOAT1KCNH2TLR8 | |
| Ammonia Solution, Strong SCHEMBL2186005 | 0.86 | MCHR1 (0.41) | MCHR1TSHRTLR8CDK9DYRK1A | |
| SCHEMBL9253185 | 0.83 | CNR2 (0.37) | TSHRCDK9DYRK1ADYRK2HTR7 | |
| SCHEMBL24306014 | 0.82 | SOAT1 (0.48) | MCHR1TSHRSOAT1KCNH2TLR8 | |
| SCHEMBL19511104 | 0.81 | CDK9 (0.39) | TSHRKCNH2CDK9DYRK1ADYRK2 | |
| SCHEMBL24305930 | 0.81 | MCHR1 (0.44) | MCHR1TSHRSOAT1KCNH2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724571-B1 | SUBSTITUTED PYRIDINE-2-ONES AND SUBSTITUTED PYRIDINE-2-THIONES AS BIOCIDES | ARCH CHEM INC (US) | 2002-01-30 | — | — | EP | claimed |
| CN-1084735-C | Substituted pyridin-2-ones and substituted pyridine-2-thiones as biocides | ARCH CHEMICAL INDUSTRY CO (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1133035-A | Substituted pyridin-2-ones and substituted pyridine-2-thiones as biocides | OLIN CORP (US) | 1996-10-09 | — | — | CN | disclosed |