SCHEMBL21860428

SCHEMBL21860428

Cc1ccc2cc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)oc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.56
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SHBG P04278 1/20 0.44
TNKS O95271 2/20 0.42
PARP1 P09874 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
PARP2 Q9UGN5 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
APP P05067 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
APAF1 O14727 1/20 0.41
USP2 O75604 1/20 0.41
RAB9A P51151 1/20 0.41
P2RY14 Q15391 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7128324 0.94 MAOB (0.51) MAOBSHBGTNKSPARP1TNKS2
SCHEMBL21860307 0.93 MAOB (0.51) MAOBKDM4EALDH1A1TP53CYP3A4
SCHEMBL21860325 0.90 MAOB (0.55) MAOBKDM4EALDH1A1TP53CYP3A4
SCHEMBL21860421 0.88 MAOB (0.74) MAOBKDM4EALDH1A1TP53CYP3A4
SCHEMBL14900851 0.88 MAOB (0.56) MAOBKDM4EALDH1A1TP53CYP3A4
SCHEMBL11711558 0.86 MAOB (0.70) MAOBKDM4EALDH1A1TP53CYP3A4
SCHEMBL11713027 0.86 MAOB (0.74) MAOBKDM4EALDH1A1TP53CYP3A4
SCHEMBL21860494 0.86 RAB9A (0.44) MAOBKDM4EALDH1A1TP53CYP3A4
SCHEMBL24368617 0.85 HDAC6 (0.47) MAOBSHBGTNKSHDAC6APP
SCHEMBL21860321 0.85 APP (0.54) MAOBKDM4EALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 US disclosed
US-20210082632-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2021-03-18 US disclosed
US-10590100-B2 Benzofuran derivatives for the treatment of CNS and other disorders Ambient Photonics, Inc. (US) 2020-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10590100-B2 Benzofuran derivatives for the treatment of CNS and other disorders PMP22, CDR2, CLN6 MAOB 489/4885KDM4E 3612/4885ALDH1A1 1925/4885
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes FDFT1, SUN2, CDC73 MAOB 2764/4885KDM4E 2392/4885ALDH1A1 352/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 MAOB 2940/4885KDM4E 1702/4885ALDH1A1 406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.