Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21860428 | 0.94 | MAOB (0.56) | MAOBSHBGAPPAPAF1USP2 | |
| SCHEMBL21860321 | 0.90 | APP (0.54) | MAOBAPPRAB9A | |
| SCHEMBL15080535 | 0.89 | APP (0.57) | MAOBSHBGAPPAPAF1USP2 | |
| SCHEMBL21860430 | 0.88 | CYP19A1 (0.48) | MAOBSHBGAPPAPAF1USP2 | |
| SCHEMBL733971 | 0.88 | MAOB (0.61) | MAOBSHBGTYRPTGS1PTGS2 | |
| SCHEMBL7117044 | 0.87 | MAOB (0.69) | MAOBAPPCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21860491 | 0.87 | S1PR1 (0.41) | MAOBSHBGAPPAPAF1USP2 | |
| SCHEMBL21860307 | 0.86 | MAOB (0.51) | MAOBSHBGAPPAPAF1USP2 | |
| SCHEMBL21860494 | 0.85 | RAB9A (0.44) | MAOBSHBGAPPAPAF1USP2 | |
| SCHEMBL21860325 | 0.83 | MAOB (0.55) | MAOBSHBGAPPAPAF1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | SHARP KABUSHIKI KAISHA (JP) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | BBOX1, DDO, OGFOD1 | MAOB 128/4885SHBG 2300/4885APP 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.