Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861525 | 0.85 | TRPA1 (0.47) | TRPA1CNR2SYK | |
| SCHEMBL17609592 | 0.81 | ADK (0.43) | TRPA1CNR2ASIC3ADK | |
| SCHEMBL21861425 | 0.80 | TRPA1 (0.47) | TRPA1CNR2SYK | |
| SCHEMBL17619545 | 0.76 | CNR2 (0.65) | CNR2 | |
| SCHEMBL30715016 | 0.72 | GRM1 (0.39) | CNR2KCNH2 | |
| SCHEMBL17609930 | 0.70 | MAP3K12 (0.43) | TRPA1CNR2ADK | |
| SCHEMBL19396087 | 0.68 | TRPA1 (0.56) | TRPA1 | |
| SCHEMBL21861422 | 0.68 | TRPA1 (0.45) | TRPA1 | |
| SCHEMBL21861548 | 0.68 | RET (0.35) | TRPA1CNR2KCNH2 | |
| SCHEMBL23843149 | 0.67 | GRIN2D (0.47) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |