Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861283 | 0.83 | TRPA1 (0.64) | TRPA1 | |
| SCHEMBL21861301 | 0.83 | TRPA1 (0.60) | TRPA1 | |
| SCHEMBL17609774 | 0.76 | TRPA1 (0.86) | TRPA1 | |
| SCHEMBL21861717 | 0.76 | TRPA1 (0.62) | TRPA1 | |
| SCHEMBL21861681 | 0.74 | TRPA1 (0.49) | TRPA1 | |
| SCHEMBL21861773 | 0.74 | TRPA1 (0.64) | TRPA1 | |
| SCHEMBL21861718 | 0.74 | TRPA1 (0.63) | TRPA1 | |
| SCHEMBL21861503 | 0.73 | TRPA1 (0.61) | TRPA1 | |
| SCHEMBL17609873 | 0.72 | TRPA1 (0.70) | TRPA1 | |
| SCHEMBL17609589 | 0.72 | TRPV3 (0.53) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |