Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609658 | 0.83 | ASIC3 (0.34) | — | |
| SCHEMBL21609686 | 0.81 | CHRNA7 (0.32) | PIM1 | |
| SCHEMBL17609864 | 0.75 | SMPD3 (0.38) | PIM1PIM3PIM2ALOX5APFEN1 | |
| SCHEMBL17619980 | 0.72 | TRPA1 (0.40) | PIM1PIM3PIM2ALOX5APFEN1 | |
| SCHEMBL21861621 | 0.69 | CHRNA7 (0.34) | — | |
| SCHEMBL21861615 | 0.68 | ASIC3 (0.40) | — | |
| SCHEMBL21861339 | 0.68 | — | — | |
| SCHEMBL21861466 | 0.62 | ASIC3 (0.41) | — | |
| SCHEMBL17609930 | 0.59 | MAP3K12 (0.43) | — | |
| SCHEMBL17609994 | 0.57 | PIM1 (0.33) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |