Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 14/20 | 0.53 |
| ▸ | XIAP | P98170 | 5/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861357 | 0.86 | TRPA1 (0.53) | TRPA1XIAPBIRC2ABL1 | |
| SCHEMBL21861626 | 0.86 | TRPA1 (0.53) | TRPA1XIAPBIRC2ABL1 | |
| SCHEMBL20390889 | 0.80 | XIAP (0.43) | TRPA1XIAPBIRC2 | |
| SCHEMBL12681451 | 0.80 | XIAP (0.43) | TRPA1XIAPBIRC2 | |
| SCHEMBL21861494 | 0.78 | TRPA1 (0.53) | TRPA1XIAPBIRC2 | |
| SCHEMBL12680085 | 0.77 | XIAP (0.41) | TRPA1XIAPBIRC2 | |
| SCHEMBL17609767 | 0.75 | TRPA1 (0.82) | TRPA1 | |
| SCHEMBL17609766 | 0.75 | TRPA1 (0.82) | TRPA1 | |
| SCHEMBL13907113 | 0.75 | XIAP (0.40) | TRPA1XIAPBIRC2ABL1 | |
| SCHEMBL12681463 | 0.73 | XIAP (0.39) | TRPA1XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |