SCHEMBL2186186

SCHEMBL2186186

CCc1cc(-c2cc(CC)c(N)c(CC)c2)cc(CC)c1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.54
POLB P06746 2/20 0.54
ALDH1A1 P00352 3/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPT P10636 2/20 0.39
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
GABRA1 P14867 3/20 0.33
GABRB2 P47870 3/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9751581 0.97 HTT (0.52) HTTPOLBALDH1A1TP53CYP3A4
Methane SCHEMBL27855766 0.97 HTT (0.52) HTTPOLBALDH1A1TP53CYP3A4
SCHEMBL29656878 0.97 HTT (0.52) HTTPOLBALDH1A1TP53CYP3A4
Formaldehyde SCHEMBL22802133 0.95 HTT (0.50) HTTPOLBALDH1A1TP53CYP3A4
SCHEMBL20572544 0.95 HTT (0.50) HTTPOLBALDH1A1TP53CYP3A4
SCHEMBL20572995 0.88 HTT (0.45) HTTPOLBALDH1A1TP53CYP3A4
SCHEMBL10979678 0.86 TDP1 (0.48) HTTPOLBALDH1A1TP53CYP3A4
SCHEMBL7615550 0.86 POLB (0.44) HTTPOLBALDH1A1TP53CYP3A4
SCHEMBL9325247 0.85 ALDH1A1 (0.59) HTTPOLBALDH1A1TP53CYP3A4
Methane SCHEMBL21294037 0.83 ALDH1A1 (0.56) HTTPOLBALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025073720-A1 RECOMBINANT HEPATITIS C VIRUS GLYCOPROTEINS, COMPOSITION AND APPLICATION(S) THEREOF Stichting Amsterdam UMC (NL) 2025-04-10 WO disclosed
US-11946872-B2 Coupon design for enhanced color sensitivity for colorimetric-based chemical analysis of liquids CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) 2024-04-02 US disclosed
EP-3679343-B1 COUPON DESIGN FOR ENHANCED COLOR SENSITIVITY FOR COLORIMETRIC-BASED CHEMICAL ANALYSIS OF LIQUIDS UNIV CLEMSON RES FOUNDATION (US) 2023-06-07 EP disclosed
US-20220397535-A1 Coupon Design for Enhanced Color Sensitivity for Colorimetric-Based Chemical Analysis of Liquids CLEMSON UNIVERSITY RESEARCH FOUNDATION 2022-12-15 US disclosed
WO-2022237924-A1 ANTIBODY BINDING TO RBD OF THE SPIKE PROTEIN OF SARS-COV-2 AND A METHOD FOR QUANTIFYING PROTECTIVE ANTIBODIES AGAINST SARS-COV-2 USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2022-11-17 WO disclosed
US-11415523-B2 Coupon design for enhanced color sensitivity for colorimetric-based chemical analysis of liquids CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) 2022-08-16 US disclosed
US-11273215-B2 Synthetic polypeptide epitope based vaccine composition BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2022-03-15 US disclosed
US-20210364444-A1 Coupon Design for Enhanced Color Sensitivity for Colorimetric-Based Chemical Analysis of Liquids UNIV CLEMSON RES FOUNDATION (US) 2021-11-25 US disclosed
EP-3679343-A1 COUPON DESIGN FOR ENHANCED COLOR SENSITIVITY FOR COLORIMETRIC-BASED CHEMICAL ANALYSIS OF LIQUIDS Clemson University Research Foundation (US) 2020-07-15 EP disclosed
CN-111050795-A Vaccine compositions based on synthetic polypeptide epitopes 巴拉特生物技术国际有限公司 2020-04-21 CN disclosed
US-4596770-A In assay using 3,3',5,5'-tetraalkylbenzidine chromogen and added N-methylpyrrolidone and peroxide, the reaction is stopped, and color intensity is measured TRAVENOL-GENETECH DIAGNOSTICS (US) 1986-06-24 US disclosed
EP-0071934-B1 METHOD FOR PREPARING A COLOR STABLE CHROMOGENIC ANALYTICAL ELEMENT MILES LABORATORIES, INC. (US) 1986-06-11 EP disclosed
WO-1985005688-A1 ASSAY OF PEROXIDASE ENZYME ACTIVITY TRAVENOL-GENETECH DIAGNOSTICS (US) 1985-12-19 WO disclosed
US-4524133-A CYSTIC FIBROSIS MILES LABORATORIES, INC. (US) 1985-06-18 US disclosed
US-4385114-A DETERMINATION OF HYDROGEN PEROXIDE OR PEROXIDASE BOEHRINGER MANNHEIM GMBH (DE) 1983-05-24 US disclosed
EP-0072450-A1 Test device for lactase activity in a meconium sample MILES LABORATORIES, INC. (US) 1983-02-23 EP disclosed
EP-0071934-A1 Method for preparing a color stable chromogenic analytical element MILES LABORATORIES, INC. (US) 1983-02-16 EP disclosed
US-4361648-A POLYMERIC MORDANT, TETRAALKYLBENZIDINE HYDROCHLORIDE, ENZYME, PEROXIDATIVELY ACTIVE MATERIAL MILES LABORATORIES, INC. (US) 1982-11-30 US disclosed
US-4273868-A GLUCOSE DETERMINATION FROM BODY FLUIDS MILES LABORATORIES, INC. (US) 1981-06-16 US disclosed
US-4224407-A USING L-LYSINE A-OXIDASE YAMASA SHOYU KABUSHIKI KAISHA (JP) 1980-09-23 US disclosed