Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.45 |
| ▸ | EZH1 | Q92800 | 3/20 | 0.45 |
| ▸ | EED | O75530 | 4/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.41 |
| ▸ | AEBP2 | Q6ZN18 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18736292 | 0.96 | EZH2 (0.43) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL18573635 | 0.82 | EZH2 (0.59) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL18844794 | 0.79 | EZH2 (0.56) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL21862652 | 0.76 | EZH2 (0.78) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL22373767 | 0.71 | EZH2 (0.62) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL3707475 | 0.70 | LMNA (0.49) | — | |
| SCHEMBL25544483 | 0.68 | EZH2 (0.57) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL19657083 | 0.68 | EZH2 (0.59) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL18715056 | 0.68 | EZH2 (0.73) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL15709860 | 0.68 | EZH2 (0.83) | EZH2EZH1EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628662-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2020-04-01 | — | — | EP | disclosed |