Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257406 | 0.80 | KMT2A (0.37) | SMN1; SMN2TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2185192 | 0.80 | CA1 (0.39) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL2185175 | 0.78 | CA1 (0.42) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL3591619 | 0.76 | CA12 (0.54) | CA12CA7CA14LMNASMN1; SMN2 | |
| SCHEMBL27748331 | 0.76 | MAPT (0.39) | LMNASMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12821513 | 0.75 | KDM4E (0.42) | ALDH1A1KDM4EMAPT | |
| SCHEMBL2187580 | 0.75 | KDM4E (0.42) | ALDH1A1KDM4EMAPT | |
| SCHEMBL83829 | 0.75 | MEN1 (0.32) | — | |
| SCHEMBL7602303 | 0.75 | CA12 (0.59) | CA12CA7CA14LMNASMN1; SMN2 | |
| SCHEMBL15693585 | 0.75 | CA12 (0.59) | CA12CA7CA14LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346507-A1 | USE OF QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES | Boehringer Ingelheim International GmbH (DE) | 2011-07-27 | — | — | EP | claimed |
| WO-2010026029-A1 | USE OF QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | claimed |
| US-4021461-A | INSECTICIDES | ZOECON CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |
| US-4012559-A | Radiation curable coating composition and precoated metal having top coat based on the same | TORAY INDUSTRIES, INC (JA) | 1977-03-15 | — | — | US | disclosed |